ATI Pathophysiology Practice Exam 2025 – 400 Free Practice Questions to Pass the Exam

The pituitary gland plays a crucial role in regulating the production of testosterone. It secretes luteinizing hormone (LH), which signals the Leydig cells in the testes to produce testosterone. This regulation is part of the hypothalamic-pituitary-gonadal axis, where the hypothalamus releases gonadotropin-releasing hormone (GnRH), stimulating the pituitary to release LH and follicle-stimulating hormone (FSH). Increased levels of testosterone then have feedback effects on both the hypothalamus and the pituitary to help maintain hormonal balance.

The adrenal gland does produce some testosterone and other androgens, but it is not the primary regulator of testosterone production. The thyroid gland is primarily involved in regulating metabolism and does not have a direct role in testosterone production. The pancreas is mainly responsible for insulin and glucagon production, which are key in glucose metabolism, rather than hormone regulation related to testosterone.