ATI Pathophysiology Practice Exam 2025 – 400 Free Practice Questions to Pass the Exam

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Why is the regulation of blood pH critical for enzymes in the body?

Enzyme activity is pH-dependent

The regulation of blood pH is critical for enzymes because enzyme activity is highly pH-dependent. Each enzyme has an optimal pH range in which it functions most effectively. Deviations from this optimal pH can lead to changes in the enzyme's three-dimensional structure, which can affect its active site and reduce its ability to catalyze reactions. Enzymes are proteins that rely on their shape for function, and pH alterations can lead to denaturation or altered enzyme activity, resulting in decreased metabolic efficiency or failure of biochemical pathways. Consequently, maintaining the appropriate blood pH is essential for proper enzymatic function and overall physiological balance. This underscores the importance of homeostasis in biological systems.

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Enzymes increase oxygen availability

Enzymes control nutrient absorption

Enzymes are only effective at low temperatures

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